Patients experiencing severe symptoms of depression at an early stage of life have a high genetic disposition to major depressive disorders (MDD) such as chronic depression, bipolar disorder, schizophrenia and other psychiatric disorders observes Brenda Penninx, PhD, Department of Psychiatry, Vrije Universiteit (VU) Medical Center in Amsterdam, Netherlands, and her team of researchers.
The group examined the genome-wide data of a total of 3331 people, of whom 1539 were diagnosed with MDD by The Netherlands Study of Depression and Anxiety (NESDA). For each patient, the researchers calculated genomic risk profile scores for MDD, bipolar disorder and schizophrenia.
The findings, published in the Biological Psychiatry, the official journal of the Society of Biological Psychiatry, highlighted the genetic similarities between subgroups of patients battling any kind of MDD based on their clinical features. The findings have given a whole new direction to the classification of diversely ranging patients suffering from MDD, which in turn may provide the much needed impetus to identify the culpable genes.
Characteristics, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM), including the onset of depression at an early age, high symptom severity score and a large number of specific symptoms, have been linked to the higher genetic load for these three psychiatric disorders.
On the other hand, no association was found between genetic risk profile scores, family history of depression, the duration of the symptoms or recurring incidences of MDD. “This study supports the idea that psychiatric disorders are heterogeneous and that the early onset and more severe forms of depression are the ones with greater heritability,” said Dr. John Krystal, Editor of Biological Psychiatry.
Depression is a chronic illness
As per the statistics by the Anxiety and Depression Association of America (ADAA), in 2014 alone, approximately 16 million adults, aged 18 years or older, had gone through at least one major bout of depression in the past year. At any given point of time, 3 out of 5 Americans, 8 out of every 1000 teens, and as many as 2 out of every 100 children might have serious depression.
Depression is one of the most common mental health problems in the United States. Sadly, many people fail to realize that a full-blown depression can be the root cause of numerous other maladies. The situation becomes worse when people do not get proper treatment despite being diagnosed with the debilitating mental condition.
Sovereign Health of San Clemente, California offers a variety of customized mental health treatment programs suited to treat a person holistically. In addition to individual and group psychotherapy, the patient can also opt for alternative therapeutic activities such as yoga, equine therapy, art therapy, mindfulness meditation and breathing techniques to regain control of his or her life.
Recovery road map
Depression must be taken seriously as it can be very damaging if left untreated. Sovereign Health provides holistic treatments for all kinds of mental health disorders as well as any underlying mental health conditions. You can call our 24/7 helpline number 866-973-7164 or chat online with our representatives who are available for your queries on mental health problems.
Whether you are looking for depression treatment centers in California or at a place closer home, we have facilities in all major places in the country. Our residential mental health treatment programs in California are among the best in the nation.